Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | BIOCARTA_KERATINOCYTE DIFFERENTIATION |
| Enrichment Score (ES) | -0.5925392 |
| Normalized Enrichment Score (NES) | -2.0183458 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010726311 |
| FWER p-Value | 0.046 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CEBPA | 1418982_at | 2979 | 1.726 | -0.1179 | No | ||
| 2 | GRB2 | 1418508_a_at 1449111_a_at | 3588 | 1.538 | -0.1294 | No | ||
| 3 | IKBKB | 1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at | 4679 | 1.239 | -0.1662 | No | ||
| 4 | NFKBIA | 1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at | 5266 | 1.113 | -0.1812 | No | ||
| 5 | TNF | 1419607_at | 5329 | 1.099 | -0.1724 | No | ||
| 6 | MAPK13 | 1448871_at | 5732 | 1.020 | -0.1800 | No | ||
| 7 | PPP2R5D | 1450560_a_at | 6249 | 0.934 | -0.1937 | No | ||
| 8 | CHUK | 1417091_at 1428210_s_at 1451383_a_at | 6264 | 0.932 | -0.1845 | No | ||
| 9 | EGFR | 1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at | 6570 | 0.873 | -0.1892 | No | ||
| 10 | MAP2K1 | 1416351_at | 6572 | 0.873 | -0.1801 | No | ||
| 11 | HOXA7 | 1449499_at | 6706 | 0.849 | -0.1772 | No | ||
| 12 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 7957 | 0.639 | -0.2276 | No | ||
| 13 | SHC1 | 1422853_at 1422854_at | 8026 | 0.627 | -0.2241 | No | ||
| 14 | PRKCA | 1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at | 8221 | 0.595 | -0.2266 | No | ||
| 15 | EGF | 1418093_a_at | 9052 | 0.465 | -0.2597 | No | ||
| 16 | MAPK14 | 1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at | 9589 | 0.387 | -0.2801 | No | ||
| 17 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 10517 | 0.241 | -0.3199 | No | ||
| 18 | PRKCD | 1422847_a_at 1442256_at | 10621 | 0.228 | -0.3222 | No | ||
| 19 | FASLG | 1418803_a_at 1449235_at | 10638 | 0.224 | -0.3205 | No | ||
| 20 | RIPK1 | 1419508_at 1439273_at 1449485_at | 12208 | -0.017 | -0.3920 | No | ||
| 21 | HRAS | 1422407_s_at 1424132_at | 12431 | -0.057 | -0.4016 | No | ||
| 22 | PRKCE | 1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at | 13855 | -0.301 | -0.4634 | No | ||
| 23 | PRKCH | 1422079_at 1434248_at | 13875 | -0.303 | -0.4611 | No | ||
| 24 | MAP2K3 | 1425456_a_at 1451714_a_at | 15187 | -0.559 | -0.5151 | No | ||
| 25 | SOS1 | 1421884_at 1421885_at 1421886_at | 15572 | -0.643 | -0.5258 | No | ||
| 26 | IKBKG | 1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at | 15672 | -0.666 | -0.5233 | No | ||
| 27 | FOS | 1423100_at | 16185 | -0.784 | -0.5384 | No | ||
| 28 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 16585 | -0.880 | -0.5474 | No | ||
| 29 | BIRC3 | 1421392_a_at 1425223_at | 17574 | -1.109 | -0.5808 | Yes | ||
| 30 | PRKCQ | 1426044_a_at | 17590 | -1.113 | -0.5698 | Yes | ||
| 31 | DAXX | 1419026_at | 17792 | -1.168 | -0.5666 | Yes | ||
| 32 | PLAT | 1415806_at 1458553_at | 18010 | -1.237 | -0.5635 | Yes | ||
| 33 | JUN | 1417409_at 1448694_at | 18344 | -1.347 | -0.5645 | Yes | ||
| 34 | ETS2 | 1416268_at 1437809_x_at 1447685_x_at | 18658 | -1.475 | -0.5632 | Yes | ||
| 35 | SP1 | 1418180_at 1448994_at 1454852_at | 19272 | -1.744 | -0.5728 | Yes | ||
| 36 | BIRC2 | 1418854_at | 19444 | -1.821 | -0.5614 | Yes | ||
| 37 | FAS | 1460251_at | 19551 | -1.886 | -0.5463 | Yes | ||
| 38 | TRAF1 | 1423602_at 1445452_at | 19721 | -2.020 | -0.5327 | Yes | ||
| 39 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 19751 | -2.036 | -0.5125 | Yes | ||
| 40 | MAP3K1 | 1424850_at | 20648 | -2.888 | -0.5230 | Yes | ||
| 41 | RELA | 1419536_a_at | 20889 | -3.265 | -0.4995 | Yes | ||
| 42 | MAPK3 | 1427060_at | 20984 | -3.442 | -0.4674 | Yes | ||
| 43 | MAP4K4 | 1422615_at 1440609_at 1448050_s_at 1459912_at | 21150 | -3.752 | -0.4353 | Yes | ||
| 44 | MAP2K4 | 1426233_at 1442679_at 1451982_at | 21293 | -4.054 | -0.3990 | Yes | ||
| 45 | TRAF2 | 1451233_at | 21335 | -4.141 | -0.3572 | Yes | ||
| 46 | RAF1 | 1416078_s_at 1425419_a_at | 21451 | -4.510 | -0.3148 | Yes | ||
| 47 | MAP2K6 | 1426850_a_at 1459292_at | 21619 | -5.264 | -0.2668 | Yes | ||
| 48 | TNFRSF1A | 1417291_at | 21839 | -8.146 | -0.1908 | Yes | ||
| 49 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21857 | -8.522 | -0.1016 | Yes | ||
| 50 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21902 | -9.953 | 0.0015 | Yes |
